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SUMMARY:Cure GABA-A | Dr. Henry Lee |  Understanding of GABAergic Signaling
DESCRIPTION:Dr. Lee made a significant discovery highlighting the role of phosphorylation-dependent turnover of the potassium chloride co-transporter\n\n\nCure GABA-A | Webinar | Understanding of GABAergic Signaling \nJoin us for an educational session with Dr. Henry Lee. \nDr. Henry Lee is a molecular neurobiologist with a specialized interest in comprehending the molecular processes governing neuronal inhibition\, brain plasticity\, and functional recovery within the context of brain development and trauma. Through the integration of molecular biology and electrophysiology techniques\, Dr. Lee made a significant discovery highlighting the role of phosphorylation-dependent turnover of the potassium chloride co-transporter KCC2 in controlling Cl- mediated GABAergic inhibition (Lee et al.\, Nat Neurosci\, 2011). Employing innovative genetic mouse models\, he further investigated a paracrine signaling mechanism crucial for critical period (CP) plasticity control (Spatazza\, Lee et al.\, Cell Rep\, 2013; Lee et al.\, Mol Psychiatry\, 2017). \nDr. Lee’s translational research extends to the realm of functional recovery post-nerve damage (Bei\, Lee et al.\, Cell\, 2016) and traumatic brain injury (Hsieh\, Lee et al.\, Cerebral Cortex\, 2016). His recent focus centers on SSADH deficiency\, a rare inborn GABA metabolic disorder. Dr. Lee is actively engaged in the development of a specialized mouse tool for SSADH\, allowing ‘on-demand’ SSADH restoration. This endeavor is directed towards contributing to the preclinical advancement of innovative therapies for SSADH deficiency. \nJoin Cure GABA-A and Dr. Henry Lee on February 8th\, 2024\, at 11:00 PM PST for an educational session. For more details\, contact us on our socials or email: monica@cureGABAa.com. \nCan’t make it in person? Don’t worry – This session will be recorded and uploaded to the Cure GABA-A YouTube channel for your convenience. \n \nJoin us in our collective mission to improve the lives of patients with GABA-A Variants and work toward a brighter future.
URL:https://curegabaa.org/event/cure-gaba-a-dr-henry-lee-understanding-of-gabaergic-signaling/
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ORGANIZER;CN="CURE GABA-A":MAILTO:info@curegabaa.org
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